SUN1

1 paper1 finding

1 lab in 1 country

Funders: Japan Society for the Promotion of Science and others

Animals1

Outcomes

1

Age-related axon initial segment shortening

downin mice1

1 study

SUN1 prevents age-related axon initial segment shortening in mice.
“Furthermore, Sun1 administration to aged neurons prevents age-related AIS shortening, excitability impairment, and brain function changes.”
Animalsneuron
Age-related decline in nuclear envelope LINC complex drives neuronal aging via axon initial segment dysfunction
EMBO reports22 May 2026

Funding

1 grant since 2024

Japan Society for the Promotion of ScienceJP¥2.9m

Elucidation of the mechanism of neuromuscular junction regeneration mediated by SUN1/2 toward the development of a treatment for sarcopenia
Japan Society for the Promotion of ScienceShimane UniversityJP¥2.9m2024–2026

Latest

1 in 12 months

EMBO Reports23 May

Age-related decline in nuclear envelope LINC complex drives neuronal aging via axon initial segment dysfunction

Experiments in miceInterventions