Stem cells from human exfoliated deciduous teeth-derived exosomes

Intervention

1 paper studies it4 findings

  • 1 lab in 1 country
  • Funders: Beijing Nova Program and 3 more
  • Animals1

Outcomes

4

Tendon repair capacity

upin rats1

1 study
  1. Stem cells from human exfoliated deciduous teeth-derived exosomes improve tendon repair capacity in rats.

    “functionally and structurally rescuing endogenous tendon regeneration and repair capacity in aged rats”

    Animalsmicrospherestendon

    Young Exosome Bio-Nanoparticles Restore Aging-Impaired Tendon Stem/Progenitor Cell Function and Reparative Capacity

    Advanced materials (Deerfield Beach, Fla.)Feb 14, 2023

Ectopic ossification

downin rats1

1 study
  1. Stem cells from human exfoliated deciduous teeth-derived exosomes decrease ectopic ossification in rats.

    “decreased ectopic bone formation, thereby functionally and structurally rescuing endogenous tendon regeneration and repair capacity in aged rats”

    Animalsmicrospherestendon

    Young Exosome Bio-Nanoparticles Restore Aging-Impaired Tendon Stem/Progenitor Cell Function and Reparative Capacity

    Advanced materials (Deerfield Beach, Fla.)Feb 14, 2023

More on Ectopic ossification

Cellular senescence

downin rats1

1 study
  1. Stem cells from human exfoliated deciduous teeth-derived exosomes decrease cellular senescence in rats.

    “local delivery of SHED-Exos-loaded microspheres confers anti-aging phenotypes, including reduced senescent cells and decreased ectopic bone formation”

    Animalsmicrospherestendon

    Young Exosome Bio-Nanoparticles Restore Aging-Impaired Tendon Stem/Progenitor Cell Function and Reparative Capacity

    Advanced materials (Deerfield Beach, Fla.)Feb 14, 2023

More on Cellular senescence

Tendon degeneration

downin mice1

1 study
  1. Stem cells from human exfoliated deciduous teeth-derived exosomes decrease tendon degeneration in mice.

    “systemic administration of SHED-Exo bio-nanoparticles retards tendon degeneration”

    Animalsnanoparticlestendon

    Young Exosome Bio-Nanoparticles Restore Aging-Impaired Tendon Stem/Progenitor Cell Function and Reparative Capacity

    Advanced materials (Deerfield Beach, Fla.)Feb 14, 2023

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