Spray-dried porcine plasma
Spray-dried porcine plasma has been studied in 3 papers since 2021: none in people yet, 3 in animals. The research so far is in animals. The newest paper, Mar 24, 2023: “Dietary supplementation with spray-dried animal plasma improves vaccine protection in aged mice”.
3 papers study it10 findingsUpdated
See all 3 papers on spray-dried porcine plasma
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Government of Catalonia and others
- 10 of 10 findings with company ties
- Animals3
What did studies of spray-dried porcine plasma find?
8Studies of spray-dried porcine plasma measured 8 outcomes; the most studied is inflammation (3 studies).
Inflammation
downin mice3
3 studies
Inflammation
downin mice3
Spray-dried porcine plasma decreases inflammation in mice (immunized and challenged with lethal shock).
“aged mice showed higher expression levels of pro-inflammatory cytokines (Il-6, Tnf-α, Ifn-γ, and Il-1β) in jejunal and (Tnf-α, and Il-1β) in lung tissues (p < 0.05), which were reduced by SDP supplementation”
Animalsimmunized and challenged with lethal shock8%4 monthsmales
Dietary supplementation with spray-dried animal plasma improves vaccine protection in aged mice
Frontiers in nutrition
Spray-dried porcine plasma decreases inflammation in mice (aged mice).
“SDP attenuated both colonic and systemic inflammation in aged mice (all p < 0.05).”
Animalsaged micespray-driedcolon and serum8% of dietfour months
Nutrients
Spray-dried porcine plasma decreases inflammation in SAMP8 mice.
“Senescence increased the expression of Mme1 and Ide1 and pro-inflammatory cytokines (Il-17 and Il-18; all p < 0.05); these changes were prevented by SDP supplementation.”
Animalsin SAMP8 micebrain8%4 months
Nutrients
IL-10
upin mice1
1 study
IL-10
upin mice1
Spray-dried porcine plasma increases IL-10 in mice (senescent mice after lethal challenge).
“in senescent mice, SDP supplementation augmented Il-4 and Il-10 expression in both tissues (p < 0.05)”
Animalssenescent mice after lethal challenge8%4 monthsmales
Dietary supplementation with spray-dried animal plasma improves vaccine protection in aged mice
Frontiers in nutrition
Survival
upin mice1
1 study
Survival
upin mice1
Spray-dried porcine plasma improves survival in mice (immunized with SEB followed by lethal shock).
“all immunized aged mice that were supplemented with SDP survived, in contrast to only 66% of those fed the control feed (p < 0.05)”
Animalsimmunized with SEB followed by lethal shock8%4 monthsmales
Dietary supplementation with spray-dried animal plasma improves vaccine protection in aged mice
Frontiers in nutrition
Cortical BDNF abundance
upin mice1
1 study
Cortical BDNF abundance
upin mice1
Spray-dried porcine plasma increases cortical BDNF abundance in mice (senescent SAMP8 mice).
“these effects were mitigated by SDP (all p < 0.05)”
Animalssenescent SAMP8 micespray-driedcerebral cortex8% of dietfour months
Nutrients
Memory impairment
downin mice1
1 study
Memory impairment
downin mice1
Spray-dried porcine plasma decreases memory impairment in mice (senescent SAMP8 mice).
“these effects were mitigated by SDP (all p < 0.05)”
Animalssenescent SAMP8 micespray-dried8% of dietfour months
Nutrients
Microglial activation markers
downin mice1
1 study
Microglial activation markers
downin mice1
Spray-dried porcine plasma decreases microglial activation markers in SAMP8 mice.
“Furthermore, in aged mice, the gene expression levels of the microglial activation markers Trem2, Ym1, and Arg1 were increased, and SDP prevented these increases (all p < 0.05).”
Animalsin SAMP8 micebrain8%4 months
Nutrients
TGFB1
upin mice1
1 study
TGFB1
upin mice1
Spray-dried porcine plasma increases TGFB1 in SAMP8 mice.
“Moreover, SDP increased Tgf-β expression (p < 0.05).”
Animalsin SAMP8 micebrain8%4 months
Nutrients
BACE1
downin mice1
1 study
BACE1
downin mice1
Spray-dried porcine plasma decreases BACE1 in SAMP8 mice.
“SDP prevented these effects of aging and reduced Bace1 levels (all p < 0.05).”
Animalsin SAMP8 micebrain8%4 months
Nutrients