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Spike-targeting t-cell-dependent bispecific iggs

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • 2 of 2 findings with company ties
  • Animals1

Outcomes

2

Body weight loss

downin mice1

1 study

  1. Spike-targeting t-cell-dependent bispecific iggs decrease body weight loss in mice.

    “improves the efficiency of treatment in preinfected mice by attenuating disease-induced weight loss and death.”

    Animalspreinfected with SARS-CoV-2

    T-Cell-Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS-CoV-2 Infection

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)20 Feb 2025

Mortality

downin mice1

1 study

  1. Spike-targeting t-cell-dependent bispecific iggs decrease mortality in mice.

    “improves the efficiency of treatment in preinfected mice by attenuating disease-induced weight loss and death.”

    Animalspreinfected with SARS-CoV-2

    T-Cell-Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS-CoV-2 Infection

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)20 Feb 2025

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