Soymilk

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country
1 finding against

Funder: National Center for Geriatrics and Gerontology
2 of 2 findings with company ties

Human trial1

Outcomes

Skeletal muscle index

upin humans1no changein humans1

1 study

Soymilk increases skeletal muscle index in humans (Mean difference in SMI change: 0.08 kg/m2 (95% CI 0.004–0.15)).
“a significant difference in the change in the SMI between the HSP and control groups was revealed for pre-frail elderly subjects”
Human trialExploratory subgroup of Japanese pre-frail individuals; compared with control soymilkhigh-soy-protein soymilkskeletal muscle12 weeksn = 58
The Effect of Routine High-Soy-Protein Soymilk Intake on the Skeletal Muscle Index (SMI) in Japanese Pre-Frail Elderly Individuals with an Ordinary Life: A Post Hoc Analysis of a Randomized Controlled Trial
Nutrients13 Dec 2025
Soymilk has no effect on skeletal muscle index in humans.
“In the overall analysis (primary combined cohort), the SMI showed no significant change between the HSP and control soymilk groups (p = 0.18)”
Human trialJapanese frail and pre-frail individuals; compared with control soymilkhigh-soy-protein soymilkskeletal muscle12 weeksn = 68
The Effect of Routine High-Soy-Protein Soymilk Intake on the Skeletal Muscle Index (SMI) in Japanese Pre-Frail Elderly Individuals with an Ordinary Life: A Post Hoc Analysis of a Randomized Controlled Trial
Nutrients13 Dec 2025

Latest

1 in 12 months

Nutrients13 Dec

The Effect of Routine High-Soy-Protein Soymilk Intake on the Skeletal Muscle Index (SMI) in Japanese Pre-Frail Elderly Individuals with an Ordinary Life: A Post Hoc Analysis of a Randomized Controlled Trial

Randomised trial in 68 peopleMuscle

Paper

Soymilk

Outcomes

Latest

The Effect of Routine High-Soy-Protein Soymilk Intake on the Skeletal Muscle Index (SMI) in Japanese Pre-Frail Elderly Individuals with an Ordinary Life: A Post Hoc Analysis of a Randomized Controlled Trial

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