Social isolation and loneliness

Exposure

1 paper2 findings

  • 1 lab in 1 country
  • Humans1

Outcomes

1

Recovery from ADL limitation

downin humans1HR 0.34

1 study
  1. Social isolation and loneliness decreases recovery from ADL limitation in humans (HR 0.34, 95% CI 0.17–0.70).

    “66% lower recovery from ADL limitation (3→1 0.34, 0.17–0.70)”

    Humanscardiometabolic multimorbidity9 yearsn = 1,731

    Isolation and loneliness linked to less independence in Chinese study

    Research Square11 Oct 2026Preprint

Associations

1

Post-disability mortality

upin humans1HR 1.57

1 study
  1. Social isolation and loneliness raises the risk of post-disability mortality in humans (HR 1.57, 95% CI 1.04–2.39).

    “higher post-disability mortality (3→4 1.57, 1.04–2.39)”

    Humanscardiometabolic multimorbidity9 yearsn = 1,731

    Isolation and loneliness linked to less independence in Chinese study

    Research Square11 Oct 2026Preprint

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Research Square

Isolation and loneliness linked to less independence in Chinese study

In adults with cardiometabolic multimorbidity, models estimated 4.83 independent years at ages 60–90 with low isolation and no loneliness, versus 0.65 with both.In adults with cardiometabolic multimorbidity, models estimated 4.83 independent years at ages 60–90 with low isolation and no loneliness, versus 0.65 with both.

Preprint: cohort study of 1,731 peoplePopulations