Social environment

4 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

2 independent labs in 2 countries

Humans3
Model organisms1

Associations

Prospective memory

upin humans1

1 study

Social environment is associated with prospective memory in humans.
“prospective memory differed between the weaker and stronger profile.”
Humansn = 19,793
Social environment profiles and cognitive outcomes: a cross-sectional latent class analysis using the Canadian Longitudinal Study on Aging
Aging & mental health3 Nov 2025

Episodic memory

upin humans1

1 study

Social environment is associated with episodic memory in humans.
“Executive function and episodic memory scores significantly differed between all three profiles”
Humansn = 19,793
Social environment profiles and cognitive outcomes: a cross-sectional latent class analysis using the Canadian Longitudinal Study on Aging
Aging & mental health3 Nov 2025

Executive function

upin humans1

1 study

Social environment is associated with executive function in humans.
“Significant associations between the social environment profiles and the three cognitive domains were observed among all statistical models (all p ≤ 0.001).”
Humansn = 19,793
Social environment profiles and cognitive outcomes: a cross-sectional latent class analysis using the Canadian Longitudinal Study on Aging
Aging & mental health3 Nov 2025

Health function

upin humans1

1 study

Social environment is associated with health function in humans (path coef. = 0.409).
“The role of social environment (path coef. =0.409) is the predominant in these pathways.”
Humansn = 2,688
Environmental and capacity drivers of health function: a full perspective of the healthy aging framework
Frontiers in public health24 Sep 2025