Molecular Therapy
RNA delivery favored human blood stem cells in mice
In humanized mice, antibody-free fat particles delivered more messenger RNA to human blood-forming stem and precursor cells than a comparison formulation.In humanized mice, antibody-free fat particles delivered more messenger RNA to human blood-forming stem and precursor cells than a comparison formulation.
Mouse studyInterventions
Who was studiedHumanized NBSGW mice, against SM-102 particles
What changedThe new particles delivered more messenger RNA to human blood-forming stem and precursor cells than SM-102 particles
The catchThe abstract did not report long-term outcomes after RNA delivery