Single-person household
Intervention1 paper5 findings
One human study links single-person households to higher cardiovascular disease, Parkinson’s disease, dementia and composite mental health outcome risks in kidney transplant recipients over a median six years, but finds no effect on mortality.
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
Funder: Ministry of Health and Welfare
- Humans1
Outcomes
1Mortality
no changein humans1
1 study
Mortality
no changein humans1
Single-person household has no effect on mortality in humans.
Humanskidney transplant recipientsmedian 6 years
Mental Health, Neurodegenerative, and Cardiovascular Health of Korean Kidney Transplant Recipients in Single-Person Households · American journal of kidney diseases : the official journal of the National Kidney Foundation · 21 Sep 2026
Associations
4Cardiovascular disease
upin humans1
1 study
Cardiovascular disease
upin humans1
Single-person household raises the risk of cardiovascular disease in humans (aHR 1.40, 95% CI 1.00-1.96).
Humanskidney transplant recipientsmedian 6 years
Mental Health, Neurodegenerative, and Cardiovascular Health of Korean Kidney Transplant Recipients in Single-Person Households · American journal of kidney diseases : the official journal of the National Kidney Foundation · 21 Sep 2026
Parkinson's disease
upin humans1
1 study
Parkinson's disease
upin humans1
Single-person household raises the risk of Parkinson's disease in humans (aHR 4.40, 95% CI 1.48-13.09).
Humanskidney transplant recipientsmedian 6 years
Mental Health, Neurodegenerative, and Cardiovascular Health of Korean Kidney Transplant Recipients in Single-Person Households · American journal of kidney diseases : the official journal of the National Kidney Foundation · 21 Sep 2026
Dementia
upin humans1
1 study
Dementia
upin humans1
Single-person household raises the risk of dementia in humans (aHR 1.68, 95% CI 1.05-2.70).
Humanskidney transplant recipientsmedian 6 years
Mental Health, Neurodegenerative, and Cardiovascular Health of Korean Kidney Transplant Recipients in Single-Person Households · American journal of kidney diseases : the official journal of the National Kidney Foundation · 21 Sep 2026
Composite mental health outcome
upin humans1
1 study
Composite mental health outcome
upin humans1
Single-person household raises the risk of composite mental health outcome in humans (aHR 1.28, 95% CI 1.02-1.60).
Humanskidney transplant recipientsmedian 6 years
Mental Health, Neurodegenerative, and Cardiovascular Health of Korean Kidney Transplant Recipients in Single-Person Households · American journal of kidney diseases : the official journal of the National Kidney Foundation · 21 Sep 2026