Sglt inhibitors

1. Sglt inhibitors activate autophagy.

   “This in turn promotes autophagy, which helps to optimize cellular integrity and prevent apoptotic cell death.”

   Review

   SGLT inhibitors for improving Healthspan and lifespan

   Progress in cardiovascular diseases·Oct 17, 2023

More on Autophagy

1. Sglt inhibitors decrease oxidative stress and ROS signaling.

   “SGLTi decreases oxidative stress and endoplasmic reticulum stress, restores of mitochondrial health, stimulates mitochondrial biogenesis, and diminishes proinflammatory and profibrotic pathways.”

   Review

   SGLT inhibitors for improving Healthspan and lifespan

   Progress in cardiovascular diseases·Oct 17, 2023

More on Oxidative stress and ROS signaling

1. Sglt inhibitors extend lifespan.

   “Studies also show that SGLTi improves overall life expectancy and reduces risks of cardiovascular death and cancer death.”

   Review

   SGLT inhibitors for improving Healthspan and lifespan

   Progress in cardiovascular diseases·Oct 17, 2023