Senescent macrophages

1 paper2 findings

1 lab in 1 country

Funders: Fundamental Research Funds for Central Universities of the Central South University and 1 more

Humans1

Outcomes

2

VEGFA

upin mice1

1 study

Senescent macrophages increase VEGFA in mice.
“Mechanistically, these senescent macrophages induce endothelial dysfunction via increasing vascular endothelial growth factor A-165B (VEGF-A165B) expression and secretion”
Animalsin senescent macrophages
Senescent Macrophages Promote Age-Related Revascularization Impairment by Increasing Antiangiogenic VEGF-A165B Expression
Aging cellApr 17, 2025

Revascularization

downin mice1

1 study

Senescent macrophages impair revascularization in mice.
“we find senescent macrophages inhibit revascularization.”
Animalsfollowing hindlimb ischemia
Senescent Macrophages Promote Age-Related Revascularization Impairment by Increasing Antiangiogenic VEGF-A165B Expression
Aging cellApr 17, 2025

Latest

Aging CellApr 17

Senescent Macrophages Promote Age-Related Revascularization Impairment by Increasing Antiangiogenic VEGF-A165B Expression

Study in peopleCellular senescence