Sclerostin-neutralizing antibody

1 paper1 finding

1 lab in 1 country

Funders: National Institute of Arthritis and Musculoskeletal and Skin Diseases and 2 more

Animals1

Outcomes

1

miR-133a-3p

downin mice1

1 study

Sclerostin-neutralizing antibody decreases miR-133a-3p in mice.
“miR-133a-3p, a key miR that inhibits bone metabolism and function, which is upregulated in accelerated skeletal aging (i.e., focal radiation) downregulated by Scl-Ab.”
AnimalsFocally radiated miceneutralizing antibodybone
MicroRNA networks associated with skeletal aging and WNT pathway modulation
Calcified tissue international25 May 2026

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Calcified Tissue International25 May

MicroRNA networks associated with skeletal aging and WNT pathway modulation

Experiments in miceInterventions