Roscovitine

1 paper studies it4 more mention it2 findings

1 lab in 1 country

Animals1

Outcomes

2

KALIRIN-7

downin rat cells1

1 study

Roscovitine decreases KALIRIN-7 in rat cells.
“All of these in vitro effects were significantly attenuated following treatment with Roscovitine.”
Cellshigh-glucose conditions
SIRT1 Attenuates Neuropathic Pain via CDK5-Kalirin-7 Signaling Pathway in Type 2 Diabetic Rats
Molecular neurobiologyMar 25, 2025

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Neuropathic pain

downin rats1

1 study

Roscovitine decreases neuropathic pain in rats.
“the thermal hyperalgesia and mechanical allodynia were markedly diminished in cohort Ros (the cohorts were administered Roscovitine).”
Animalstype 2 diabetic neuropathic pain (STZ)
SIRT1 Attenuates Neuropathic Pain via CDK5-Kalirin-7 Signaling Pathway in Type 2 Diabetic Rats
Molecular neurobiologyMar 25, 2025

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Latest

Molecular NeurobiologyMar 25

SIRT1 Attenuates Neuropathic Pain via CDK5-Kalirin-7 Signaling Pathway in Type 2 Diabetic Rats

Experiments in ratsSirtuin signaling

Cancer Cell InternationalDec 8

Identification and validation of cellular senescence patterns to predict clinical outcomes and immunotherapeutic responses in lung adenocarcinoma

Study in peopleBiomarkers

Amino AcidsAug 14

Epibrassinolide prevents tau hyperphosphorylation via GSK3β inhibition in vitro and improves Caenorhabditis elegans lifespan and motor deficits in combination with roscovitine

Experiments in model organismsInterventions

Biology of ReproductionJun 27

Role of AMP-activated protein kinase during postovulatory aging of mouse oocytes†

Experiments in cellsMechanisms

Neurobiology of DiseaseJun 27

CK2 inhibition confers functional protection to young and aging axons against ischemia by differentially regulating the CDK5 and AKT signaling pathways

Experiments in cellsMechanisms