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RNase-mediated digestion of EV cargo

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: 1 observational study in people

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Ministero della Salute
  • Humans1

Outcomes

1

Cellular senescence

downin human cells1

1 study

  1. RNase-mediated digestion of EV cargo prevents cellular senescence in human cells (completely).

    “RNase-mediated digestion of EV cargo completely abrogated tubular senescence and EndMT.”

    Cellsin vitro

    Extracellular vesicles derived from patients with antibody-mediated rejection induce tubular senescence and endothelial to mesenchymal transition in renal cells

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

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