QRFP-26

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funders: National Institute of Diabetes and Digestive and Kidney Diseases and 3 more
  • Animals1

Outcomes

3

Prepro-orexin mRNA

downin rats1

1 study
  1. QRFP-26 decreases prepro-orexin mRNA in rats.

    “QRFP-26administration did not alter the expression of prepro-NPY, AgRP or POMC mRNA in the MBH, but decreased prepro-orexin mRNA in the LH”

    Animalsin ovariectomized femalesfemales

    The hypothalamic neuropeptide, QRFP, regulates high fat diet intake in female Long-Evans rats following ovariectomy

    Peptides21 Jan 2023

More on Prepro-orexin mRNA

Weight gain

upin rats1

1 study
  1. QRFP-26 increases weight gain in rats.

    “Sub-chronic, continuous administration of QRFP-26 increased HFD intake and weight gain following OVX.”

    Animalsin ovariectomized ratsfemales

    The hypothalamic neuropeptide, QRFP, regulates high fat diet intake in female Long-Evans rats following ovariectomy

    Peptides21 Jan 2023

High fat diet intake

upin rats1

1 study
  1. QRFP-26 increases high fat diet intake in rats.

    “When administered prior to EB treatment, QRFP-26 increased HFD intake.”

    Animalsin ovariectomized rats prior to EB treatmentfemales

    The hypothalamic neuropeptide, QRFP, regulates high fat diet intake in female Long-Evans rats following ovariectomy

    Peptides21 Jan 2023

Latest