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Porphyromonas gingivalis ii

Exposure

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab
  • Humans1

Associations

3

Type 2 diabetes

no changein humans1OR 1.48

1 study

  1. Porphyromonas gingivalis ii is associated with type 2 diabetes in humans (OR 1.48 (95% CI 0.72-3.06)).

    “ORs (95% CI) for T2D, poor glycemic control, and HT in the PgII-positive group were 1.48 (0.72-3.06), 2.39 (1.03-5.57), and 1.75 (1.08-82), respectively.”

    Humansn = 1,015

    Association between Porphyromonas gingivalis II and Diabetes, Poor Glycemic Control, and Hypertension

    ADA Scientific Sessions 2025 abstract13 Jun 2025

More on Type 2 diabetes

Hypertension

upin humans1OR 1.75

1 study

  1. Porphyromonas gingivalis ii is associated with hypertension in humans (OR 1.75 (95% CI 1.08-82)).

    “ORs (95% CI) for T2D, poor glycemic control, and HT in the PgII-positive group were 1.48 (0.72-3.06), 2.39 (1.03-5.57), and 1.75 (1.08-82), respectively.”

    Humansn = 1,015

    Association between Porphyromonas gingivalis II and Diabetes, Poor Glycemic Control, and Hypertension

    ADA Scientific Sessions 2025 abstract13 Jun 2025

More on Hypertension

Poor glycemic control

upin humans1OR 2.39

1 study

  1. Porphyromonas gingivalis ii is associated with poor glycemic control in humans (OR 2.39 (95% CI 1.03-5.57)).

    “ORs (95% CI) for T2D, poor glycemic control, and HT in the PgII-positive group were 1.48 (0.72-3.06), 2.39 (1.03-5.57), and 1.75 (1.08-82), respectively.”

    Humansn = 1,015

    Association between Porphyromonas gingivalis II and Diabetes, Poor Glycemic Control, and Hypertension

    ADA Scientific Sessions 2025 abstract13 Jun 2025

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