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Plasma exosomes from exercised donors

Plasma exosomes from exercised donors has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 9, 2026: “Blood particles from active rats change gene activity in older rats”.

Intervention

1 paper studies it3 findingsUpdated

See all 1 papers on plasma exosomes from exercised donors

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: US Department of Veterans Affairs
  • Animals1

What did studies of plasma exosomes from exercised donors find?

3

Studies of plasma exosomes from exercised donors measured 3 outcomes: Parkinson's disease signaling pathway, BDNF and Activated microglia gene expression.

Parkinson's disease signaling pathway

downin rats1

1 study

  1. Plasma exosomes from exercised donors decrease Parkinson's disease signaling pathway in rats (compared with controls).

    “Parkinson's disease signaling pathways were most significantly downregulated in astrocytes”

    Animalscompared with controlsplasma exosomes from exercised donorsastrocytesmales

    Blood particles from active rats change gene activity in older rats

    Frontiers in aging neuroscience

BDNF

upin rats1

1 study

  1. Plasma exosomes from exercised donors increase BDNF in rats (compared with controls).

    “The levels of exercise-associated peptides brain-derived neurotrophic factor (BDNF) and irisin were also elevated.”

    Animalscompared with controlsplasma exosomes from exercised donorsbasal gangliamales

    Blood particles from active rats change gene activity in older rats

    Frontiers in aging neuroscience

More on BDNF

Activated microglia gene expression

downin rats1

1 study

  1. Plasma exosomes from exercised donors decrease activated microglia gene expression in rats (compared with controls).

    “rats that received exosomes from exercised donors had lower gene expression associated with activated microglia”

    Animalscompared with controlsplasma exosomes from exercised donorsbasal gangliamales

    Blood particles from active rats change gene activity in older rats

    Frontiers in aging neuroscience

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months
Frontiers in Aging Neuroscience

Blood particles from active rats change gene activity in older rats

Nine sedentary male rats received brain infusions for seven days; particles from exercised donors prompted molecular changes consistent with exercise adaptations.Nine sedentary male rats received brain infusions for seven days; particles from exercised donors prompted molecular changes consistent with exercise adaptations.

Rat studyInterventions
Paper

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