Picolinic acid
Intervention1 paper2 findings
- Animals1
Outcomes
2Caudal fin regeneration
upin zebrafish1Very low certainty
1 study
Caudal fin regeneration
upin zebrafish1Very low certainty
Picolinic acid increases caudal fin regeneration in zebrafish.
“Regeneration in Groups 2 and 3 was more advanced than in Group 1, with stronger staining by β-galactosidase.”
Animalsin aged zebrafish treated with PIC in water + 25 or 75 mg/kg oral gavagecaudal fin8 weeksn = 15
Gerotherapeutic compound picolinic acid supports locomotor function and bone health in aged zebrafish · GSA 2025 abstract · 31 Dec 2025
Swimming performance
upin zebrafish1Very low certainty
1 study
Swimming performance
upin zebrafish1Very low certainty
Picolinic acid improves swimming performance in zebrafish (44.5 m/min vs 31.7 m/min, p = 0.01).
“Group 2 showed the highest swimming speed (44.5 m/min), followed by Group 1 (34.7 m/min) (p = 0.01 and p = 0.09, respectively) than the control group (31.7 m/min).”
AnimalsPIC in water + 25 mg/kg oral gavagePIC in water + 25 mg/kg oral gavage8 weeksn = 15
Gerotherapeutic compound picolinic acid supports locomotor function and bone health in aged zebrafish · GSA 2025 abstract · 31 Dec 2025