Phenylalanine-betaxanthin

Phenylalanine-betaxanthin has been studied in 2 papers since 2020: none in people yet, 2 in animals. The research so far is in animals. The newest paper, Dec 9, 2022: “Characterization of betalain-loaded liposomes and its bioactive potential in vivo after ingestion”.

Intervention

2 papers study it4 findingsUpdated

PubChem

See all 2 papers on phenylalanine-betaxanthin

At a glance

The findings reach worms or flies, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Worms or flies: a single group. Cells, mice and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: Fundación Séneca and others
  • Model organisms2

What did studies of phenylalanine-betaxanthin find?

3

Studies of phenylalanine-betaxanthin measured 3 outcomes: lifespan, oxidative stress and ROS signaling and lipid and ceramide metabolism.

Lifespan

upin worms2+17% to +22%

2 studies
  1. Phenylalanine-betaxanthin extends lifespan in worms (+21.8%).

    “phenylalanine-betaxanthin was the most effective betalain by increasing the lifespan of C. elegans by 21.8%”

    Model organismsliposomes

    Characterization of betalain-loaded liposomes and its bioactive potential in vivo after ingestion

    Food chemistry

  2. Phenylalanine-betaxanthin extends lifespan in worms (up to 16.53%).

    “increasing the lifespan of C. elegans up to 16.82%, 16.65%, 16.53%, and 12.93%, respectively”

    Model organismspure

    Betalain health-promoting effects after ingestion in Caenorhabditis elegans are mediated by DAF-16/FOXO and SKN-1/Nrf2 transcription factors

    Food chemistry

Oxidative stress and ROS signaling

downin worms1

1 study
  1. Phenylalanine-betaxanthin decreases oxidative stress and ROS signaling in worms.

    “Phenylalanine-betaxanthin and indoline carboxylic acid-betacyanin encapsulated at concentrations of 25 and 500 μM managed to reduce lipid accumulation and oxidative stress in the nematodes”

    Model organismsliposomes25 and 500 μM

    Characterization of betalain-loaded liposomes and its bioactive potential in vivo after ingestion

    Food chemistry

More on Oxidative stress and ROS signaling

Lipid and ceramide metabolism

downin worms1

1 study
  1. Phenylalanine-betaxanthin decreases lipid and ceramide metabolism in worms.

    “Phenylalanine-betaxanthin and indoline carboxylic acid-betacyanin encapsulated at concentrations of 25 and 500 μM managed to reduce lipid accumulation”

    Model organismsliposomes25 and 500 μM

    Characterization of betalain-loaded liposomes and its bioactive potential in vivo after ingestion

    Food chemistry

More on Lipid and ceramide metabolism

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