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Phase-locked acoustic stimulation

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Heidi Seiler-Stiftung and 5 more
  • Human trial1

Outcomes

1

Episodic memory

upin humans1

1 study

  1. Phase-locked acoustic stimulation improves episodic memory in humans.

    “In both groups, PLAS induced a significant electrophysiological response in both voltage- and time-frequency analyses, and memory performance improved in association with the magnitude of this response.”

    Human trialin healthy older adults and older adults with cognitive impairment3 consecutive stimulation nights

    Multi-night acoustic stimulation is associated with better sleep, amyloid dynamics, and memory in older adults with cognitive impairment

    GeroScienceMay 14, 2024

Associations

1

Aβ42/Aβ40 ratio

upin humans1

1 study

  1. Phase-locked acoustic stimulation is associated with Aβ42/Aβ40 ratio in humans.

    “Only in the CI sample, stronger electrophysiological responses were significantly associated with improving post-intervention Aβ42/Aβ40 ratios.”

    Human trialin older adults with cognitive impairment3 consecutive stimulation nightsn = 16

    Multi-night acoustic stimulation is associated with better sleep, amyloid dynamics, and memory in older adults with cognitive impairment

    GeroScienceMay 14, 2024

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