Peripheral nerve block

Peripheral nerve block has been studied in 4 papers since 2023: 2 observational studies in people, 2 reviews; 1 in the past year. The newest paper, Oct 21, 2026: “Association of peripheral nerve block plus general anesthesia with MMSE-Defined early postoperative cognitive decline in older orthopedic patients: A prospective observational pilot study”.

Exposure

4 papers study it3 findingsUpdated

1 new paper in 30 daysSee all 4

1 of its findings points the other way.

  • 1 lab
  • 1 finding against
  • Humans2

What did studies of Peripheral nerve block find?

2

Studies of Peripheral nerve block measured 2 outcomes; the most studied are mortality (1 study) and perioperative neurocognitive disorder (1).

Mortality

downin humans1

1 study
  1. Peripheral nerve block decreases mortality in humans.

    “Peripheral nerve blocks including pericapsular nerve group (PENG) blocks have shown benefit in lowering morbidity and mortality.”

    Reviewin hip fragility fractures

    Improving morbidity and mortality in hip fragility fractures

    Current opinion in anaesthesiology

Perioperative neurocognitive disorder

no changein humans1

1 study
  1. Peripheral nerve block has no effect on perioperative neurocognitive disorder in humans.

    “PNB did not reduce the incidence of PND in the elderly hip fracture population comprising patients with intact cognition and those with pre-existing dementia or cognitive impairment”

    Reviewin population comprising patients with intact cognition and pre-existing dementia or cognitive impairment

    Peripheral Nerve Block and Peri-operative Neurocognitive Disorders in Older Patients With Hip Fractures: A Systematic Review With Meta-analysis

    Geriatric orthopaedic surgery & rehabilitation

More on Perioperative neurocognitive disorder

What is Peripheral nerve block linked with?

1

Studies link Peripheral nerve block with 1 measure, most often perioperative neurocognitive disorder (1 study).

Perioperative neurocognitive disorder

downin humans1

1 study
  1. Peripheral nerve block lowers the risk of perioperative neurocognitive disorder in humans.

    “PNB reduced the incidence of PND in older patients with intact cognition (RR = .61; 95% CI = .41 to .91; P = .02; I2 = 0%).”

    Reviewin older patients with intact cognition

    Peripheral Nerve Block and Peri-operative Neurocognitive Disorders in Older Patients With Hip Fractures: A Systematic Review With Meta-analysis

    Geriatric orthopaedic surgery & rehabilitation

More on Perioperative neurocognitive disorder

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months