Peripheral blood mononuclear cell secretome

Peripheral blood mononuclear cell secretome has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Oct 31, 2026: “Inflammatory immune cell groups expand in aging mouse skin”.

Intervention

1 paper studies it2 findingsUpdated

1 new paper in 30 daysSee all 1

None of its findings points the other way.

  • 1 lab
  • Animals1

What did studies of Peripheral blood mononuclear cell secretome find?

1

Studies of Peripheral blood mononuclear cell secretome measured 1 outcome; the most studied are fibrosis-associated fibroblast gene expression (1 study).

Fibrosis-associated fibroblast gene expression

downin mice1

1 study
  1. Peripheral blood mononuclear cell secretome decreases fibrosis-associated fibroblast gene expression in mice (ex vivo treatment of aged skin).

    “shifted the macrophage compartment toward a younger-like composition and down-regulated fibrosis-associated fibroblast genes.”

    Animalsex vivo treatment of aged skinsecretome of γ-irradiated peripheral blood mononuclear cellsskinmales

    Inflammatory immune cell groups expand in aging mouse skin

    Frontiers in cell and developmental biology

More on Fibrosis-associated fibroblast gene expression

What is Peripheral blood mononuclear cell secretome linked with?

1

Studies link Peripheral blood mononuclear cell secretome with 1 measure, most often skin macrophage composition (1 study).

Skin macrophage composition

mixedin mice1

1 study
  1. Peripheral blood mononuclear cell secretome is associated with skin macrophage composition in mice (ex vivo treatment of aged skin).

    “Ex vivo treatment of aged skin with the secretome of γ-irradiated peripheral blood mononuclear cells (PBMC-sec) shifted the macrophage compartment toward a younger-like composition”

    Animalsex vivo treatment of aged skinsecretome of γ-irradiated peripheral blood mononuclear cellsskinmales

    Inflammatory immune cell groups expand in aging mouse skin

    Frontiers in cell and developmental biology

More on Skin macrophage composition

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months
Frontiers in Cell and Developmental Biology

Inflammatory immune cell groups expand in aging mouse skin

Experiments on skin removed from older mice suggested that substances released by blood immune cells could partly counter age-related changes.Experiments on skin removed from older mice suggested that substances released by blood immune cells could partly counter age-related changes.

Accepted, not yet published: mouse studySkin