Fibrosis-associated fibroblast gene expression

There is 1 paper on fibrosis-associated fibroblast gene expression in aging research: none in people yet, 1 in animals. The newest story, Oct 31, 2026: “Inflammatory immune cell groups expand in aging mouse skin”.

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Peripheral blood mononuclear cell secretome

downin mice1

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  1. Peripheral blood mononuclear cell secretome decreases fibrosis-associated fibroblast gene expression in mice (ex vivo treatment of aged skin).

    “shifted the macrophage compartment toward a younger-like composition and down-regulated fibrosis-associated fibroblast genes.”

    Animalsex vivo treatment of aged skinsecretome of γ-irradiated peripheral blood mononuclear cellsskinmales

    Inflammatory immune cell groups expand in aging mouse skin

    Frontiers in cell and developmental biology

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Frontiers in Cell and Developmental Biology

Inflammatory immune cell groups expand in aging mouse skin

Experiments on skin removed from older mice suggested that substances released by blood immune cells could partly counter age-related changes.Experiments on skin removed from older mice suggested that substances released by blood immune cells could partly counter age-related changes.

Accepted, not yet published: mouse studySkin