Periodontal disease

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: National Institute of Dental and Craniofacial Research

Humans1

Associations

Stroke

upin humans1OR 2.8

1 study

Periodontal disease raises the risk of stroke in humans (OR 2.8).
“Incidence odds ratios adjusted for established cardiovascular risk factors were 1.5, 1.9, and 2.8 for bone loss and total CHD, fatal CHD, and stroke, respectively.”
Humansmalesn = 1,147
Periodontal Disease and Cardiovascular Disease
Journal of periodontology1 Oct 1996

Funding

3 grants since 2024

National Institute of Dental and Craniofacial ResearchUS$1m

Latest

Journal of Periodontology1 Oct