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Penta-N-methylated peptide

Penta-N-methylated peptide has been studied in 1 paper since 2009: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Dec 24, 2009: “Poly-N-methylated amyloid beta-peptide (Abeta) C-terminal fragments reduce Abeta toxicity in vitro and in Drosophila melanogaster”.

Intervention

1 paper studies it2 findingsUpdated

More peptides

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Model organisms1

What did studies of Penta-N-methylated peptide find?

2

Studies of Penta-N-methylated peptide measured 2 outcomes; the most studied are locomotor activity (1 study) and lifespan (1).

Locomotor activity

upin flies1

1 study

  1. Penta-N-methylated peptide improves locomotor activity in flies.

    “This penta-N-methylated peptide moreover increased life span and locomotor activity in Drosophila melanogaster flies overexpressing human Abeta(1-42).”

    Model organismsoverexpressing human Abeta(1-42)

    Poly-N-methylated amyloid beta-peptide (Abeta) C-terminal fragments reduce Abeta toxicity in vitro and in Drosophila melanogaster

    Journal of medicinal chemistry

Lifespan

upin flies1

1 study

  1. Penta-N-methylated peptide extends lifespan in flies.

    “This penta-N-methylated peptide moreover increased life span and locomotor activity in Drosophila melanogaster flies overexpressing human Abeta(1-42).”

    Model organismsoverexpressing human Abeta(1-42)

    Poly-N-methylated amyloid beta-peptide (Abeta) C-terminal fragments reduce Abeta toxicity in vitro and in Drosophila melanogaster

    Journal of medicinal chemistry

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