PD-1-KO-HROBO1-CAR-NK-92 cells

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funder: Hunan Provincial Innovation Foundation for Postgraduate
  • Animals1

Outcomes

1

Tumor growth

downin mice1

1 study
  1. PD-1-KO-HROBO1-CAR-NK-92 cells decrease tumor growth in mice.

    “had a significant inhibitory effect on tumor growth in the mouse xenograft model.”

    Animalsmouse xenograft model

    Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer

    Cancer gene therapy5 Sep 2025

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