PARP3 inhibitors

Intervention

1 paper1 finding

  • 1 lab
  • Animals1

Outcomes

1

Intestinal organoid growth

downin mouse cells1

1 study
  1. PARP3 inhibitors decrease intestinal organoid growth in mouse cells.

    “Parp3 inhibitors slowed down organoids’ growth of the middle age.”

    Cellsorganoids from middle-aged miceintestinal crypt organoids

    Fall of Parp3 restrains Lgr5+ stem cells proliferation and mucosal renovation in intestinal aging

    Research Square24 Feb 2022Preprint

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