Pancreatic stellate cells

1. Pancreatic stellate cells protect against survival in human cells.

   “PSCs partially prevented cytokine-induced stress in both systems, but beneficial effects were stronger in composite capsules.”

   Cellsin microencapsulated human islets exposed to cytokines

   Pancreatic stellate cells support human pancreatic β-cell viability in vitro and enhance survival of immunoisolated human islets exposed to cytokines

   Materials today. Bio·Jun 18, 2024

1. Pancreatic stellate cells inhibit inflammation in human cells.

   “PSCs were associated with upregulation of β-cell mitochondrial activity and suppression of inflammatory gene expression.”

   Cellsin β-cells co-cultured with PSCs under cytokine stress

   Pancreatic stellate cells support human pancreatic β-cell viability in vitro and enhance survival of immunoisolated human islets exposed to cytokines

   Materials today. Bio·Jun 18, 2024

More on Inflammation

1. Pancreatic stellate cells increase mitochondrial content in human cells.

   “PSCs were associated with upregulation of β-cell mitochondrial activity and suppression of inflammatory gene expression.”

   Cellsin β-cells co-cultured with PSCs under cytokine stress

   Pancreatic stellate cells support human pancreatic β-cell viability in vitro and enhance survival of immunoisolated human islets exposed to cytokines

   Materials today. Bio·Jun 18, 2024

More on Mitochondrial content

1. Pancreatic stellate cells protect against cell viability in human cells.

   “co-culturing PSCs with human CM β-cells and human cadaveric islets had rescuing effects on cytokine-induced stress.”

   Cellsunder cytokine-induced inflammatory stress

   Pancreatic stellate cells support human pancreatic β-cell viability in vitro and enhance survival of immunoisolated human islets exposed to cytokines

   Materials today. Bio·Jun 18, 2024