P16HIGH cell elimination

P16HIGH cell elimination has been studied in 1 paper since 2020: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Sep 18, 2020: “Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo”.

Intervention

1 paper studies it2 findingsUpdated

See all 1

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: Core Research for Evolutional Science and Technology and 8 more
  • Animals1

What did studies of P16HIGH cell elimination find?

2

Studies of P16HIGH cell elimination measured 2 outcomes; the most studied are inflammation (1 study) and hepatic lipidosis (1).

Inflammation

downin mice1

1 study
  1. P16HIGH cell elimination decreases inflammation in mice.

    “elimination of p16high cells ameliorated nonalcoholic steatohepatitis-related hepatic lipidosis and immune cell infiltration”

    Animalsnonalcoholic steatohepatitis modelliver

    Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo

    Cell metabolism

More on Inflammation

Hepatic lipidosis

downin mice1

1 study
  1. P16HIGH cell elimination decreases hepatic lipidosis in mice.

    “elimination of p16high cells ameliorated nonalcoholic steatohepatitis-related hepatic lipidosis and immune cell infiltration”

    Animalsnonalcoholic steatohepatitis modelliver

    Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo

    Cell metabolism

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