Oral PCSK9 inhibitors
Intervention1 paper3 findings
Outcomes
3Adverse events
no changein humans1High certainty
1 study
Adverse events
no changein humans1High certainty
Oral PCSK9 inhibitors have no effect on adverse events in humans.
Review
Dose-stratified lipid-lowering efficacy and safety of oral PCSK9 inhibitors: a systematic review and meta-analysis · Journal of cardiovascular medicine (Hagerstown, Md.) · 1 Sep 2026
Apolipoprotein B
downin humans1High certainty
1 study
Apolipoprotein B
downin humans1High certainty
Oral PCSK9 inhibitors decrease Apolipoprotein B in humans.
Review
Dose-stratified lipid-lowering efficacy and safety of oral PCSK9 inhibitors: a systematic review and meta-analysis · Journal of cardiovascular medicine (Hagerstown, Md.) · 1 Sep 2026
LDL cholesterol
downin humans1High certainty
1 study
LDL cholesterol
downin humans1High certainty
Oral PCSK9 inhibitors decrease LDL cholesterol in humans.
Review
Dose-stratified lipid-lowering efficacy and safety of oral PCSK9 inhibitors: a systematic review and meta-analysis · Journal of cardiovascular medicine (Hagerstown, Md.) · 1 Sep 2026