Open surgical repair
Open surgical repair has been studied in 12 papers since 2021: 12 observational studies in people. The newest paper, Sep 1, 2025: “Age Related Trends and Long Term Survival in Elective Abdominal Aortic Aneurysms: A Comparison of Endovascular versus Open Repair”.
12 papers study it6 findingsUpdated
“OSR (aHR, 1.43; 95% CI, 1.19-1.73) was associated with increased 1-year mortality when compared with EVAR.”
1 of its findings points the other way.
- 5 independent labs in 3 countries
- 1 finding against
- Funders: National Institute for Health Research and 2 more
- Humans12
What did studies of Open surgical repair find?
3Studies of Open surgical repair measured 3 outcomes; the most studied are mortality (1 study), anxiety/depression (1) and health-related quality of life (1).
Mortality
no changein humans1HR 1.14
1 study
Mortality
no changein humans1HR 1.14
Open surgical repair was not clearly linked with mortality in humans (elective abdominal aortic aneurysm repair) (HR 1.14, 95% CI 0.94 - 1.39).
“No statistically significant differences were found in the < 70 years (HR 1.14, 95% CI 0.94 - 1.39) and ≥ 80 years (HR 0.88, 95% CI 0.68 - 1.14) age groups.”
Humanselective abdominal aortic aneurysm repair
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Anxiety/depression
downin humans1
1 study
Anxiety/depression
downin humans1
Open surgical repair is linked with lower anxiety/depression in humans (-0.214 (95% c.i. -0.326 to -0.101), P < 0.001).
“Anxiety/Depression decreased after open surgical repair (-0.214 (95% c.i. -0.326 to -0.101), P < 0.001).”
Humans
Longitudinal health-related quality of life in people with thoracic aortic aneurysms
The British journal of surgery
Health-related quality of life
downin humans1
1 study
Health-related quality of life
downin humans1
Open surgical repair is linked with worse health-related quality of life in humans (0.474 (95% c.i. 0.364 to 0.583), P < 0.001).
“Six weeks after open surgical repair, the impairment in health-related quality of life was greater (Mobility 0.492 (95% c.i. 0.314 to 0.669), Self-Care 0.474 (95% c.i. 0.364 to 0.583)”
Humans6 weeks
Longitudinal health-related quality of life in people with thoracic aortic aneurysms
The British journal of surgery
What is Open surgical repair linked with?
2Studies link Open surgical repair with 2 measures, most often mortality (2 studies) and 30-day mortality (1).
Mortality
upin humans2OR 2.46
2 studies
Mortality
upin humans2OR 2.46
Open surgical repair is linked with a higher risk of mortality in humans following ruptured abdominal aortic aneurysm repair (aHR 1.43, 95% CI 1.19-1.73).
“OSR (aHR, 1.43; 95% CI, 1.19-1.73) was associated with increased 1-year mortality when compared with EVAR.”
Humansfollowing ruptured abdominal aortic aneurysm repairn = 5,806
The association between frailty and outcomes following ruptured abdominal aortic aneurysm repair
Journal of vascular surgery
Open surgical repair is linked with a higher risk of mortality in humans (suprarenal and thoracoabdominal aortic aneurysms) (OR 2.46, P = 0.0001).
“type of repair (OSR versus FEVAR, OR 2.46; P = 0.0001)”
Humanssuprarenal and thoracoabdominal aortic aneurysms
Annals of vascular surgery
30-day mortality
upin humans1
1 study
30-day mortality
upin humans1
Open surgical repair is linked with a higher risk of 30-day mortality in humans (abdominal aortic aneurysm repair) (40.9% vs 7.2%, P < .001).
“The patients who had died within 30 days were significantly more likely to have undergone OSR than EVAR (40.9% vs 7.2%; P < .001).”
Humansabdominal aortic aneurysm repair
Journal of vascular surgery