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One-carbon metabolites

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: Japan Society for the Promotion of Science
  • 2 of 2 findings with company ties
  • Animals1

Outcomes

2

Dedifferentiation markers

downin mouse cells1

1 study

  1. One-carbon metabolites decrease dedifferentiation markers in mouse cells.

    “the intervention, composed of one-carbon metabolites, reduces some dedifferentiation markers without losing the lineage identity”

    Cellssomatic differentiated cells

    Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice

    Cell reports. Medicine19 Mar 2024

More on Dedifferentiation markers

Muscle regeneration

upin mice1

1 study

  1. One-carbon metabolites improve muscle regeneration in mice.

    “Moreover, the intervention enabled accelerated repair after muscle injury in young and aged mice.”

    Animalsmuscle injury

    Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice

    Cell reports. Medicine19 Mar 2024

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