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Nontoxic rnas

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Brain Research Foundation and 4 more
  • Humans1

Outcomes

1

Aβ42-induced cell death

downin cells1

1 study

  1. Nontoxic rnas protect against Aβ42-induced cell death in cells.

    “Cells depleted of nontoxic sRNAs are sensitized to Aβ42-induced cell death, and reintroducing nontoxic RNAs is protective.”

    CellsAβ42-exposed cells depleted of nontoxic sRNAs

    Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer’s disease and aging

    bioRxiv (Cold Spring Harbor Laboratory)Sep 10, 2022Preprint

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