Nomega-hydroxy-nor-l-arginine

Intervention

1 paper studies it3 findings

  • 1 lab in 1 country
  • Funders: Austrian Science Fund and 4 more
  • Animals1

Outcomes

3

Cellular senescence

downin mice1

1 study
  1. Nomega-hydroxy-nor-l-arginine inhibits cellular senescence in mice.

    “norNOHA prevented aging-associated intestinal barrier dysfunction, low grade endotoxemia and delayed the onset of senescence in peripheral tissue e.g., liver.”

    Animalsliver

    Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and 'inflammaging'

    Redox biology

More on Cellular senescence

Endotoxemia

downin mice1

1 study
  1. Nomega-hydroxy-nor-l-arginine prevents endotoxemia in mice.

    “norNOHA prevented aging-associated intestinal barrier dysfunction, low grade endotoxemia and delayed the onset of senescence in peripheral tissue”

    Animals

    Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and 'inflammaging'

    Redox biology

More on Endotoxemia

Intestinal barrier dysfunction

downin mice1

1 study
  1. Nomega-hydroxy-nor-l-arginine prevents intestinal barrier dysfunction in mice.

    “Treatment with the arginase inhibitor norNOHA prevented aging-associated intestinal barrier dysfunction”

    Animalssmall intestine

    Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and 'inflammaging'

    Redox biology

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