NNC0385-0434

Intervention1 paper1 finding

Outcomes

1

LDL-C

downin humans1High certainty

1 study

NNC0385-0434 decreases LDL-C in humans (-61.8 pp, 95% CI -78.1 to -45.5).
Reviewversus placebo in hypercholesterolaemia100 mg
Comparative efficacy and safety of orally administered PCSK9 inhibitors in patients with Hypercholesterolaemia: a dose-stratified systematic review and network meta-analysis · Endocrine · 6 Oct 2026

Latest

1

EndocrineReviewYesterday

Comparative efficacy and safety of orally administered PCSK9 inhibitors in patients with Hypercholesterolaemia: a dose-stratified systematic review and network meta-analysis