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Nitroxyl donor

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: none in people yet, 1 in cells

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Council of Scientific and Industrial Research, India and 5 more
  • Cells1

Outcomes

1

Oxidative stress and ROS signaling

downin cells1

1 study

  1. Nitroxyl donor decreases oxidative stress and ROS signaling in cells.

    “In a radiation-induced senescence model, the HNO donor suppressed reactive oxygen species (ROS) in a hydrogen sulfide (H2S)-dependent manner.”

    Cellsradiation-induced senescence model

    β-Galactosidase-activated nitroxyl (HNO) donors provide insights into redox cross-talk in senescent cells

    Chemical communications (Cambridge, England)

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