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Nerve block

Nerve block has been studied in 5 papers since 2021: 4 observational studies in people, 1 review. The newest paper, Jul 27, 2023: “Patients' recovery of mobility and return to original residence after hip fracture are associated with multiple modifiable components of hospital service organisation: the REDUCE record-linkage cohort study in England and Wales”.

Exposure

5 papers study it3 findingsUpdated

MeSH

See all 5

“use of preoperative nerve blocks was associated with lower risk (OR, 0.88; 95% CI, 0.81-0.95).”
Risk Factors and 120-Day Functional Outcomes of Delirium After Hip Fracture Surgery: A Prospective Cohort Study Using the UK National Hip Fracture Database (NHFD)Journal of the American Medical Directors Association2023doi:10.1016/j.jamda.2023.02.008

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 3 independent labs in 1 country
  • Funders: National Institute for Health Research and others
  • 1 of 3 findings with company ties
  • Humans4

What did studies of Nerve block find?

1

Studies of Nerve block measured 1 outcome; the most studied are mobility (1 study).

Mobility

upin humans1

1 study

  1. Nerve block improves mobility in humans (7% [95%CI:1-12%]).

    “(ii) general anaesthesia was usually accompanied by a nerve block (7% [95%CI:1-12%]”

    Humansafter hip fracture120 daysn = 56,959

    Patients' recovery of mobility and return to original residence after hip fracture are associated with multiple modifiable components of hospital service organisation: the REDUCE record-linkage cohort study in England and Wales

    BMC geriatrics

What is Nerve block linked with?

2

Studies link Nerve block with 2 measures, most often delirium (1 study) and mortality (1).

Delirium

downin humans1OR 0.88

1 study

  1. Nerve block lowers the risk of delirium in humans (OR 0.88, 95% CI 0.81-0.95).

    “use of preoperative nerve blocks was associated with lower risk (OR, 0.88; 95% CI, 0.81-0.95).”

    Humanspostoperative hip fracture patients

    Risk Factors and 120-Day Functional Outcomes of Delirium After Hip Fracture Surgery: A Prospective Cohort Study Using the UK National Hip Fracture Database (NHFD)

    Journal of the American Medical Directors Association

More on Delirium

Mortality

downin humans1HR 0.86

1 study

  1. Nerve block is associated with mortality in humans (HR=0.86 (95% CI 0.77 to 0.96); p=0.043).

    “Nerve blocks performed in both the emergency department (ED) and the operating theater (OT) were associated with reduced long-term mortality”

    Humansmedian follow-up 21 months

    Association of anesthesia and analgesia with long-term mortality after hip fracture surgery: an analysis of the Australian and New Zealand hip fracture registry

    Regional anesthesia and pain medicine

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