Femoral nerve block

Femoral nerve block has been studied in 5 papers since 2021: 3 observational studies in people, 2 reviews; 1 in the past year. The newest paper, Dec 17, 2025: “Ultrasound guided femoral nerve blocks as a compulsory pain protocol in femoral neck fractures”.

Exposure

5 papers study it5 findingsUpdated Dec 17, 2025

See all 5

“Patients undergoing FNB had significantly better 3-day CAS compared to standard care (mean [SD], 8.72 [3.42] vs 7.33 [2.62]; mean difference, 1.38 [95%CI; 0.03 - 2.74]; p = 0.048)”

Early recovery of basic mobility under femoral nerve block after hip fracture surgery - A propensity score matched pilot studyInjury2021doi:10.1016/j.injury.2021.07.028

None of its findings points the other way.

2 independent labs in 3 countries

Funder: National Institute for Health Research

Humans3

What did studies of Femoral nerve block find?

Studies of Femoral nerve block measured 3 outcomes; the most studied are preoperative pain (1 study), length of hospital stay (1) and cumulated ambulation score (1).

Preoperative pain

downin humans1

1 study

Femoral nerve block decreases preoperative pain in humans (1.46 ± 2.49 vs 1.82 ± 2.59, P = 0.001).
“those receiving US-guided FNB had significantly lower preoperative VAS pain scores (1.46 ± 2.49 vs 1.82 ± 2.59, P = 0.001)”
Humanspreoperativen = 1,577
Ultrasound guided femoral nerve blocks as a compulsory pain protocol in femoral neck fractures
World journal of orthopedicsDec 17, 2025

Length of hospital stay

no changein humans1

1 study

Femoral nerve block has no effect on length of hospital stay in humans (p = 0.65).
“Length of hospital stay did not significantly differ among the two groups (p = 0.65).”
Human trialhip fracture surgeryn = 78
Early recovery of basic mobility under femoral nerve block after hip fracture surgery - A propensity score matched pilot study
InjuryJul 23, 2021

Cumulated ambulation score

upin humans1

1 study

Femoral nerve block improves cumulated ambulation score in humans (mean difference, 1.38 [95%CI; 0.03 - 2.74]; p = 0.048).
“Patients undergoing FNB had significantly better 3-day CAS compared to standard care (mean [SD], 8.72 [3.42] vs 7.33 [2.62]; mean difference, 1.38 [95%CI; 0.03 - 2.74]; p = 0.048)”
Human trialhip fracture surgerysingle injection20ml of 0.2%n = 78
Early recovery of basic mobility under femoral nerve block after hip fracture surgery - A propensity score matched pilot study
InjuryJul 23, 2021

What is Femoral nerve block linked with?

Studies link Femoral nerve block with 2 measures, most often mortality (1 study) and rehospitalization (1).

Mortality

downin humans1

1 study

Femoral nerve block lowers the risk of mortality in humans (16% vs 32%, P < 0.001).
“lower mortality (16% vs 32%, P < 0.001) compared to standard analgesia”
Humans6 monthsn = 1,577
Ultrasound guided femoral nerve blocks as a compulsory pain protocol in femoral neck fractures
World journal of orthopedicsDec 17, 2025

Rehospitalization

downin humans1

1 study

Femoral nerve block lowers the risk of rehospitalization in humans (0.99 ± 1.96 vs 1.46 ± 2.34, P < 0.001).
“reduced rehospitalization rates (0.99 ± 1.96 vs 1.46 ± 2.34, P < 0.001)”
Humans6 monthsn = 1,577
Ultrasound guided femoral nerve blocks as a compulsory pain protocol in femoral neck fractures
World journal of orthopedicsDec 17, 2025