Fascia iliaca block
Fascia iliaca block has been studied in 2 papers since 2021: 1 trial in people, 1 review; 1 in the past year. The newest paper, Dec 1, 2025: “Ultrasound-Guided Regional Anesthesia by Emergency Physicians for Hip Fractures and Delirium: A Randomized Clinical Trial”.
2 papers study it5 findingsUpdated
“For our primary outcome, odds of delirium among patients in the treatment group were reduced (odds ratio, 0.72; 95% CI, 0.57-0.93).”
None of its findings points the other way.
- 1 lab in 1 country
- Human trial1
Studies in people
1 study gave fascia iliaca block to people and measured what changed.
down: Lowers the risk of delirium
no change: Has no effect on delirium duration
down: Decreases pain
Randomized trial732 people483 female [69.6%]median [IQR] age, 81.0 [74.0-88.0] years7 days
Patients aged 65 years and older with a surgically treated hip fracture
JAMA network open, Dec 1, 2025
What did studies of Fascia iliaca block find?
2Studies of Fascia iliaca block measured 2 outcomes; the most studied are pain (1 study) and delirium duration (1).
Pain
downin humans1
1 study
Pain
downin humans1
Fascia iliaca block decreases pain in humans.
“The mean (SD) pain score at 30 minutes after the block decreased by 3.1 points, from a baseline of 5.5 (2.7) of 10 points, and in 107 nerve blocks (57.5%), patients experienced a 50% or greater reduction in pain.”
Human trial7 daysn = 186
JAMA network open
Fascia iliaca block decreases pain in humans (57.5% with >=50% pain reduction).
“most nerve blocks were effective (107 nerve blocks [57.5%]with ≥50% pain reduction)”
Human trialhip fracturen = 186
JAMA network open
Delirium duration
no changein humans1
1 study
Delirium duration
no changein humans1
Fascia iliaca block has no effect on delirium duration in humans.
“There was no reduction in the duration of delirium (incident rate ratio, 0.92; 95% CI, 0.67-1.25).”
Human trial7 daysn = 732
JAMA network open
What is Fascia iliaca block linked with?
1Studies link Fascia iliaca block with 1 measure, most often delirium (1 study).
Delirium
downin humans1OR 0.72
1 study
Delirium
downin humans1OR 0.72
Fascia iliaca block lowers the risk of delirium in humans.
“For our primary outcome, odds of delirium among patients in the treatment group were reduced (odds ratio, 0.72; 95% CI, 0.57-0.93).”
Human trial7 daysn = 732
JAMA network open
Fascia iliaca block lowers the risk of delirium in humans (OR 0.72, 95% CI 0.57-0.93).
“delirium risk in the intervention group was reduced (odds ratio, 0.72; 95% CI, 0.57-0.93)”
Human trialhip fracturen = 694
JAMA network open