Natural killer cells

1. Natural killer cells decrease cellular senescence in cells.

   “NK cell treatment also significantly decreased levels of senescence markers and senescence-associated secretory phenotypes (SASPs) in three senescent adipose tissues when culturing them together.”

   Cellsadipose tissue

   Combining adoptive NK cell infusion with a dopamine-releasing peptide reduces senescent cells in aged mice

   Cell death & disease·Apr 5, 2022

2. Natural killer cells decrease cellular senescence in humans.

   “we observed the downregulation of senescence-related genes by adoptive infusion of natural killer (NK) cells in 26 cases in peripheral blood CD3+ T cells.”

   Human trialperipheral bloodn = 26

   Combining adoptive NK cell infusion with a dopamine-releasing peptide reduces senescent cells in aged mice

   Cell death & disease·Apr 5, 2022

More on Cellular senescence

1. Natural killer cells decrease senescent cells in human cells.

   “assess highly efficient and selective killing of senescent cells by primary NK cells enriched via our method”

   Cellsin co-cultureprimary human NK cells enriched from peripheral blood

   Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells

   Aging·Mar 4, 2022