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N1-ACETYL-5-METHOXYKYNURAMINE

Intervention

1 paper2 findings

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Japan Society for the Promotion of Science and 1 more
  • Animals1

Outcomes

2

PSD-95

upin mice1

1 study

  1. N1-ACETYL-5-METHOXYKYNURAMINE increases PSD-95 in mice.

    “The expression levels of phosphorylated cAMP response element binding protein (CREB) and PSD-95 in whole hippocampal tissue were significantly increased with AMK treatment.”

    Animalsin hippocampal tissuehippocampus

    N1-Acetyl-5-methoxykynuramine, which decreases in the hippocampus with aging, improves long-term memory via CaMKII/CREB phosphorylation

    Journal of pineal research1 Jan 2024

More on PSD-95

Phosphorylated CREB

upin mice1

1 study

  1. N1-ACETYL-5-METHOXYKYNURAMINE increases phosphorylated CREB in mice.

    “The expression levels of phosphorylated cAMP response element binding protein (CREB) and PSD-95 in whole hippocampal tissue were significantly increased with AMK treatment.”

    Animalsin hippocampal tissuehippocampus

    N1-Acetyl-5-methoxykynuramine, which decreases in the hippocampus with aging, improves long-term memory via CaMKII/CREB phosphorylation

    Journal of pineal research1 Jan 2024

More on Phosphorylated CREB

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