N-acetylcarnosine

1 paper5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Outcomes

Vasodilation

upin mice1

1 study

N-acetylcarnosine improves vasodilation in mice.
“prevents decline in adiposity, diastolic function, vasodilation, muscle strength, and bone density”
Animals6 monthsfemales
N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival
bioRxiv : the preprint server for biology5 Sep 2025Preprint

Diastolic function

upin mice1

1 study

N-acetylcarnosine improves diastolic function in mice.
“prevents decline in adiposity, diastolic function, vasodilation, muscle strength, and bone density”
Animals6 monthsfemales
N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival
bioRxiv : the preprint server for biology5 Sep 2025Preprint

Bone density

upin mice1

1 study

N-acetylcarnosine improves bone density in mice.
“prevents decline in adiposity, diastolic function, vasodilation, muscle strength, and bone density”
Animals6 monthsfemales
N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival
bioRxiv : the preprint server for biology5 Sep 2025Preprint

Muscle strength

upin mice1

1 study

N-acetylcarnosine improves muscle strength in mice.
“N-acetylcarnosine prevents decline in adiposity, diastolic function, vasodilation, muscle strength, and bone density”
Animals6 monthsfemales
N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival
bioRxiv : the preprint server for biology5 Sep 2025Preprint

Lifespan

upin mice1+50%

1 study

N-acetylcarnosine extends lifespan in mice (~50%).
“improved survival by ~50% in female mice”
Animals6 monthsfemales
N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival
bioRxiv : the preprint server for biology5 Sep 2025Preprint

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Paper

bioRxiv5 Sep

N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival

Preprint: experiments in miceInterventions

Paper