Mycobacterium leprae
1 paper3 findings
- 1 lab in 1 country
- Funders: Medical Research Council and 4 more
- Animals1
Outcomes
3Cellular senescence
no changein D. novemcinctus1
1 study
Cellular senescence
no changein D. novemcinctus1
Mycobacterium leprae has no effect on cellular senescence in D. novemcinctus.
“with minimal change in senescence and tumorigenic genes”
Animalsliver
Cell reports. MedicineNov 15, 2022
Fibrosis
no changein D. novemcinctus1
1 study
Fibrosis
no changein D. novemcinctus1
Mycobacterium leprae has no effect on fibrosis in D. novemcinctus.
“ML-infected livers are microarchitecturally and functionally normal without damage, fibrosis, or tumorigenesis.”
Animalsliver
Cell reports. MedicineNov 15, 2022
Total liver/body weight ratio
upin D. novemcinctus1
1 study
Total liver/body weight ratio
upin D. novemcinctus1
Mycobacterium leprae increases total liver/body weight ratio in D. novemcinctus.
“ML reprogram the entire liver and significantly increase total liver/body weight ratio by increasing healthy liver lobules”
Animalsliver
Cell reports. MedicineNov 15, 2022
Latest
Cell Reports Medicine
In vivo partial reprogramming by bacteria promotes adult liver organ growth without fibrosis and tumorigenesis
Experiments in animalsEpigenetic regulation of gene expression