MW151

MW151 has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest paper, Mar 31, 2026: “Glial cytokine modulation improves sleep and circadian disruption in female SAA knock-in mice of Alzheimer's-related pathology”.

Intervention

1 paper studies it3 findingsUpdated

PubChem

See all 1 papers on MW151

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: National Institute on Aging and 1 more
  • 3 of 3 findings with company ties
  • Animals1

What did studies of MW151 find?

3

Studies of MW151 measured 3 outcomes; the most studied are amyloid-beta (1 study), TNF-alpha (1) and sleep (1).

Amyloid-beta

no changein mice1

1 study
  1. MW151 showed no clear effect on amyloid-beta in mice.

    “MW151 increased light-phase sleep and reduced cortical TNF-α without altering amyloid beta (Aβ) accumulation.”

    Animalsbrain2.5 mg/kg, every other day6 weeksfemales

    Glial cytokine modulation improves sleep and circadian disruption in female SAA knock-in mice of Alzheimer's-related pathology

    Alzheimer's & dementia : the journal of the Alzheimer's Association

More on Amyloid-beta

TNF-alpha

downin mice1

1 study
  1. MW151 decreases TNF-alpha in mice.

    “MW151 increased light-phase sleep and reduced cortical TNF-α without altering amyloid beta (Aβ) accumulation.”

    Animalscortex2.5 mg/kg, every other day6 weeksfemales

    Glial cytokine modulation improves sleep and circadian disruption in female SAA knock-in mice of Alzheimer's-related pathology

    Alzheimer's & dementia : the journal of the Alzheimer's Association

More on TNF-alpha

Sleep

upin mice1

1 study
  1. MW151 improves sleep in mice.

    “MW151 increased light-phase sleep and reduced cortical TNF-α without altering amyloid beta (Aβ) accumulation.”

    Animalsbrain2.5 mg/kg, every other day6 weeksfemales

    Glial cytokine modulation improves sleep and circadian disruption in female SAA knock-in mice of Alzheimer's-related pathology

    Alzheimer's & dementia : the journal of the Alzheimer's Association

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months