Murine coronavirus infection

Murine coronavirus infection has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Oct 31, 2026: “Mouse coronavirus hastened bone loss in osteoporotic mice”.

Exposure

1 paper studies it4 findingsUpdated

1 new paper in 30 daysSee all 1

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: CNPq and 1 more
  • Animals1

What did studies of Murine coronavirus infection find?

4

Studies of Murine coronavirus infection measured 4 outcomes; the most studied are osteoclast-associated marker expression (1 study), osteoclast differentiation and activity (1) and bone loss (1).

Osteoclast-associated marker expression

upin mouse cells1

1 study
  1. Murine coronavirus infection increases osteoclast-associated marker expression in mouse cells (cells derived from sham-operated and ovariectomized mice).

    “In vitro, MHV-A59 infection enhanced the expression of osteoclast-associated markers, including Rank, Traf6, Nfac1, and cathepsin K”

    Cellscells derived from sham-operated and ovariectomized miceMHV-A59bone marrow-derived macrophages and osteoclastsfemales

    Mouse coronavirus hastened bone loss in osteoporotic mice

    bioRxivPreprint

More on Osteoclast-associated marker expression

Osteoclast differentiation and activity

upin mice1

1 study
  1. Murine coronavirus infection increases osteoclast differentiation and activity in mice.

    “These alterations were associated with increased osteoclast differentiation and activity”

    AnimalsMHV-A59females

    Mouse coronavirus hastened bone loss in osteoporotic mice

    bioRxivPreprint

Bone loss

upin mice1

1 study
  1. Murine coronavirus infection increases bone loss in mice (non-osteoporotic mice).

    “in non-osteoporotic animals, infection induced significant bone loss at later stages (60 dpi)”

    Animalsnon-osteoporotic miceMHV-A59femur60 days post-infectionfemales

    Mouse coronavirus hastened bone loss in osteoporotic mice

    bioRxivPreprint

Bone resorption

upin mice1

1 study
  1. Murine coronavirus infection increases bone resorption in mice (ovariectomy-induced osteoporosis).

    “infection accelerated bone resorption in OVX mice during the acute phase (5 dpi)”

    Animalsovariectomy-induced osteoporosisMHV-A59femur5 days post-infectionfemales

    Mouse coronavirus hastened bone loss in osteoporotic mice

    bioRxivPreprint

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 01 paper in 12 months
bioRxiv

Mouse coronavirus hastened bone loss in osteoporotic mice

In an experiment in female mice, infection accelerated bone breakdown at five days in animals with osteoporosis; mice without osteoporosis showed bone loss at 60 days.In an experiment in female mice, infection accelerated bone breakdown at five days in animals with osteoporosis; mice without osteoporosis showed bone loss at 60 days.

Preprint: mouse studyBones and joints