Multimodal therapeutic approach
1 paper3 findings
- 1 lab in 1 country
- Funder: Google
Associations
3Urine protein-to-creatinine ratio
downin humans1
1 study
Urine protein-to-creatinine ratio
downin humans1
Multimodal therapeutic approach is associated with urine protein-to-creatinine ratio in humans (>16,000 mg/g to ~6,200 mg/g).
“Over 14 months, her serum creatinine stabilized at 1.45 mg/dL, MPO titers decreased to 28 AI, and proteinuria improved to ~6,200 mg/g.”
HumansOverlapping ANCA-associated vasculitis, diabetic nephropathy, and IgA nephropathy14 monthsfemales
Cureus13 Sep 2026
MPO antibody titer
downin humans1
1 study
MPO antibody titer
downin humans1
Multimodal therapeutic approach is associated with MPO antibody titer in humans (677 AI to 28 AI).
“Over 14 months, her serum creatinine stabilized at 1.45 mg/dL, MPO titers decreased to 28 AI, and proteinuria improved to ~6,200 mg/g.”
HumansOverlapping ANCA-associated vasculitis, diabetic nephropathy, and IgA nephropathy14 monthsfemales
Cureus13 Sep 2026
Serum creatinine
downin humans1
1 study
Serum creatinine
downin humans1
Multimodal therapeutic approach is associated with serum creatinine in humans (Peak 5.2 mg/dL; stabilized at 1.45 mg/dL).
“Over 14 months, her serum creatinine stabilized at 1.45 mg/dL, MPO titers decreased to 28 AI, and proteinuria improved to ~6,200 mg/g.”
HumansOverlapping ANCA-associated vasculitis, diabetic nephropathy, and IgA nephropathy14 monthsfemales
Cureus13 Sep 2026