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Multimodal brain monitoring

Multimodal brain monitoring has been studied in 1 paper since 2021: 1 trial in people. The newest paper, Jul 15, 2021: “Management Based on Multimodal Brain Monitoring May Improve Functional Connectivity and Post-operative Neurocognition in Elderly Patients Undergoing Spinal Surgery”.

Intervention

1 paper studies it3 findingsUpdated

See all 1

“Mean post-operative MoCA score was higher in Group I (24.80 ± 2.09) than in Group C (22.56 ± 2.24) (p = 0.04)”
Management Based on Multimodal Brain Monitoring May Improve Functional Connectivity and Post-operative Neurocognition in Elderly Patients Undergoing Spinal SurgeryFrontiers in aging neuroscience2021doi:10.3389/fnagi.2021.705287

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab
  • Funder: Beijing Municipal Health Commission
  • Human trial1

Studies in people

1 study gave multimodal brain monitoring to people and measured what changed.

  • up: Improves cognitive function24.80 ± 2.09 vs 22.56 ± 2.24, p = 0.04

    no change: Has no effect on perioperative neurocognitive disorder28.57 vs. 16.67%; p = 0.47

    up: Increases functional connectivityp < 0.05

    Randomized trial≥65 years7 days after surgery

    Older adults; elective spinal surgery with general anesthesia

    Frontiers in aging neuroscience, Jul 15, 2021

What did studies of Multimodal brain monitoring find?

3

Studies of Multimodal brain monitoring measured 3 outcomes; the most studied are functional connectivity (1 study), perioperative neurocognitive disorder (1) and cognitive function (1).

Functional connectivity

upin humans1

1 study

  1. Multimodal brain monitoring increases functional connectivity in humans (p < 0.05).

    “FC between the left hippocampus and left orbital inferior frontal gyrus (FG), left middle FG, left superior temporal gyrus, and left precentral gyrus was enhanced (p < 0.05)”

    Human trialelective spinal surgery with general anesthesiabrain7 days after surgery

    Management Based on Multimodal Brain Monitoring May Improve Functional Connectivity and Post-operative Neurocognition in Elderly Patients Undergoing Spinal Surgery

    Frontiers in aging neuroscience

More on Functional connectivity

Perioperative neurocognitive disorder

no changein humans1

1 study

  1. Multimodal brain monitoring has no effect on perioperative neurocognitive disorder in humans (28.57 vs. 16.67%; p = 0.47).

    “with no difference in PND incidence between groups (28.57 vs. 16.67%; p = 0.47)”

    Human trialelective spinal surgery with general anesthesia7 days after surgery

    Management Based on Multimodal Brain Monitoring May Improve Functional Connectivity and Post-operative Neurocognition in Elderly Patients Undergoing Spinal Surgery

    Frontiers in aging neuroscience

More on Perioperative neurocognitive disorder

Cognitive function

upin humans1

1 study

  1. Multimodal brain monitoring improves cognitive function in humans (24.80 ± 2.09 vs 22.56 ± 2.24, p = 0.04).

    “Mean post-operative MoCA score was higher in Group I (24.80 ± 2.09) than in Group C (22.56 ± 2.24) (p = 0.04)”

    Human trialelective spinal surgery with general anesthesia7 days after surgery

    Management Based on Multimodal Brain Monitoring May Improve Functional Connectivity and Post-operative Neurocognition in Elderly Patients Undergoing Spinal Surgery

    Frontiers in aging neuroscience

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