MTM-guided multidomain intervention

Intervention1 paper5 findings

  • Human trial1

Outcomes

5

Depressive symptoms

downin humans1Very low certainty

1 study
  1. MTM-guided multidomain intervention decreases depressive symptoms in humans.

    Human trialmild cognitive impairment12 weeks

    Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model · Research Square · 10 Sep 2026 · Preprint

Frailty

downin humans1Very low certainty

1 study
  1. MTM-guided multidomain intervention decreases frailty in humans.

    Human trialmild cognitive impairment12 weeks

    Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model · Research Square · 10 Sep 2026 · Preprint

Cognitive function

upin humans1Very low certainty

1 study
  1. MTM-guided multidomain intervention improves cognitive function in humans.

    Human trialmild cognitive impairment12 weeks

    Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model · Research Square · 10 Sep 2026 · Preprint

Adherence

upin humans1Very low certainty

1 study
  1. MTM-guided multidomain intervention improves adherence in humans.

    Human trialmild cognitive impairment12 weeks

    Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model · Research Square · 10 Sep 2026 · Preprint

Recruitment

upin humans1Very low certainty

1 study
  1. MTM-guided multidomain intervention improves recruitment in humans (73.3% vs. 40.0%).

    Human trialmild cognitive impairment12 weeks

    Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model · Research Square · 10 Sep 2026 · Preprint

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