AgingResearch.NewsJoin free

ML141

Intervention

1 paper studies it3 findings

PubChemChEBI

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

3

Inflammation

downin mice1

1 study

  1. ML141 decreases inflammation in mice.

    “treatment with ML141 in animal models, a Cdc42 inhibitor, reduced cellular senescence and ameliorated lung injury and inflammation.”

    Animalsin animal modelslung

    Cdc42 improve SARS-CoV-2 spike protein-induced cellular senescence through activating of Wnt/β-Catenin signaling pathway

    Frontiers in cellular and infection microbiology

More on Inflammation

Lung injury

downin mice1

1 study

  1. ML141 decreases lung injury in mice.

    “treatment with ML141 in animal models, a Cdc42 inhibitor, reduced cellular senescence and ameliorated lung injury and inflammation.”

    Animalsin animal modelslung

    Cdc42 improve SARS-CoV-2 spike protein-induced cellular senescence through activating of Wnt/β-Catenin signaling pathway

    Frontiers in cellular and infection microbiology

Cellular senescence

downin mice1

1 study

  1. ML141 decreases cellular senescence in mice.

    “treatment with ML141 in animal models, a Cdc42 inhibitor, reduced cellular senescence and ameliorated lung injury and inflammation.”

    Animalsin animal modelslung

    Cdc42 improve SARS-CoV-2 spike protein-induced cellular senescence through activating of Wnt/β-Catenin signaling pathway

    Frontiers in cellular and infection microbiology

More on Cellular senescence

Latest

Related