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miR-302A-induced human neural stem cells

miR-302A-induced human neural stem cells has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Feb 14, 2023: “MiR-302-Induced anti-aging neural stem cells enhance cognitive function and extend lifespan”.

Intervention

1 paper studies it4 findingsUpdated

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Natural Science Foundation of Shandong Province and 1 more
  • Animals1

What did studies of miR-302A-induced human neural stem cells find?

4

Studies of miR-302A-induced human neural stem cells measured 4 outcomes; the most studied are oxidative stress and ROS signaling (1 study), fatigue resistance (1) and lifespan (1).

Oxidative stress and ROS signaling

downin human cells1

1 study

  1. miR-302A-induced human neural stem cells protect against oxidative stress and ROS signaling in human cells.

    “These cells showed delayed aging and increased resistance to oxidative stress compared to wild-type cells.”

    Cellsin vitro compared to wild-type cells

    MiR-302-Induced anti-aging neural stem cells enhance cognitive function and extend lifespan

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

More on Oxidative stress and ROS signaling

Fatigue resistance

upin mice1

1 study

  1. miR-302A-induced human neural stem cells improve fatigue resistance in mice.

    “increased fatigue resistance, and improved hair regeneration and reproductive capacity.”

    Animalssenescence-accelerated micehippocampus

    MiR-302-Induced anti-aging neural stem cells enhance cognitive function and extend lifespan

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

Lifespan

upin mice1+34%

1 study

  1. miR-302A-induced human neural stem cells extend lifespan in mice (+34%).

    “prolonged lifespan by 34%”

    Animalssenescence-accelerated micehippocampus

    MiR-302-Induced anti-aging neural stem cells enhance cognitive function and extend lifespan

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

Cognitive function

upin mice1

1 study

  1. miR-302A-induced human neural stem cells improve cognitive function in mice.

    “Implanting them into the hippocampus of senescence-accelerated mice improved cognitive performance in severe Alzheimer’s”

    Animalssenescence-accelerated mice with severe Alzheimer'shippocampus

    MiR-302-Induced anti-aging neural stem cells enhance cognitive function and extend lifespan

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

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